We have been following the progress on CAR-T cells over the past few years. The recent result reported in Science Daily is of special import. Namely:
In an early clinical trial, 33 out of 35 (94 percent) patients had
clinical remission of multiple myeloma upon receiving a new type of
immunotherapy -- chimeric antigen receptor (CAR) T cells targeting
B-cell maturation protein or BCMA. Most patients had only mild side
effects.
Namely, find a target on the desired cell and then create a "smart bomb" the CAR-T cell, and then set it loose. It seems to be working much more effectively now. It still has some "carpet bombing effects" but this may very well change the paradigm for cancer treatment.
Namely, find a surface target, then construct a patient specific attack element, then let the immune system loose. Very worth while to follow!
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A blog containing opinion and analysis in a wide array of areas including the economy, health care, broadband and international relations.
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- Florham Park, NJ, United States
- Terry has spent most of his career in industry, half in corporate executive positions, and half involved in his start ups. He started on the Faculty and Staff at MIT in 1967 and was there until 1975, and he had returned to MIT from 2005 to 2012 to assist groups of doctoral and post doc students. Terry has focused on a broad set of industries from cable, to satellite, wireless, and even health care software and medical imaging. Terry has published extensively in a broad set of areas as well as having written several books. Terry has returned to Medicine on Boards at Columbia University Medical Center. Copyright 2008-2024 Terrence P McGarty all rights reserved. NOTE: This blog contains personal opinions of the author and is not meant in any manner to provide professional advice, medical advice, legal advice, financial advice. Reliance on any of the opinions contained herein is done at the risk of the user. For publications see: https://www.researchgate.net/profile/Terrence_Mcgarty
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