Amazon is a great company. Really. I now get almost all personal and business purchases from them.
Now compare them to almost any health care entity, insurer to nurse. Amazon sees me as a customer. The current health care folks see me as an interruption to their personal world. I pay Amazon for service, in health care that nexus is gone.
If I have a problem with an Amazon transaction, I even get a call within a hour to remedy it! Try that with any healthcare provider.
For example I have a health care intermediary selected by a company bought by that man in Omaha who thinks he knows everything. This intermediary has a Better Business Profile that is just a step above Satan! One reads tales of poor old lady retiree taking forever to even get the phone answered and their claims denied for no reason.
Amazon and of course Bezos likes its customers and treats them with dignity. So why not get into healthcare. Get your medical care insurance from Amazon, choose your urologist from Amazon, look at the number of stars for your choice, compare prices.
This could be a great improvement! OK so Bezos and the WaPo are a bit wacky, the rest of what he does is fantastic. There is 18% of the economy just sitting there. Whole Foods is a millennial hangout, but everyone needs health care sometime.
So Mr. Bezos, I could set this up in a heart beat for you. Just give me a call!
Wednesday, June 28, 2017
Coding:Programmer as Typing:Secretary
Back in the 1970 the old Bell Telephone Companies were under pressure to have more women in management. The solution was simple. Make them programmers. Take them out of the typing pool and make them Cobol programmers.
Silicon Valley types are too young to remember Cobol but it was the business language of the 60s. Fortran was scientific. C was just starting to be thought of. I first learned FAP, Fortran Assembly Programming where we loaded registers with bits.
Now the wizards of Silicon Valley have a new Trojan Horse. Instead of training young folks in typing and shorthand, we will train them in coding. See the trend? Katherine Gibbs graduates of the new millennium.
Thus the NY Times notes:
Silicon Valley types are too young to remember Cobol but it was the business language of the 60s. Fortran was scientific. C was just starting to be thought of. I first learned FAP, Fortran Assembly Programming where we loaded registers with bits.
Now the wizards of Silicon Valley have a new Trojan Horse. Instead of training young folks in typing and shorthand, we will train them in coding. See the trend? Katherine Gibbs graduates of the new millennium.
Thus the NY Times notes:
Computer
science is also essential to American tech companies, which have become
heavily reliant on foreign engineers. Mr. Trump’s efforts to limit
immigration make Code.org’s teach-Americans-to-code agenda even more
attractive to the industry. In a few short years, Code.org has raised more than $60 million ...,
along with individual tech executives and foundations. It has helped to
persuade two dozen states to change their education policies and laws... while creating free introductory coding lessons,
called Hour of Code, which more than 100 million students worldwide have
tried. Along
the way, Code.org has emerged as a new prototype for Silicon Valley
education reform: a social-media-savvy entity that pushes for education
policy changes, develops curriculums, offers online coding lessons and
trains teachers — touching nearly every facet of the education supply
chain.
Is this just a Trojan Horse for the "training" of cheap labor. Or is it just another way for the NY Times to insert Trump in every paragraph?
But really, the algorithm to optimize train flow into and out of Penn Station is NOT programming and those being trained to "code" will not have the skills to develop such optimization. They will become the typists of the 21st century. The more we have the cheaper they become.
I always remember the NYNEX VP of MIS, a tough Irish woman, who when hearing Bob Kahn speak of the Internet and its potential in 1990 told me that I and Bob were fools, and why did we waste her time! That was an example of "training".
Labels:
Commentary
Tuesday, June 27, 2017
Plants and CRISPR
So much of the CRISPR wars have focused on human intervention. However the impact in the plant world is extraordinary. After all we have to eat.
Dupont Pioneer had announced a major effort worth the look.
DuPont Pioneer today announced waxy corn hybrids as its first commercial agricultural product developed through the application of CRISPR-Cas enabled advanced breeding technology. This next generation of elite waxy corn hybrids is expected to be available to U.S. growers within five years, pending field trials and regulatory reviews. "We’re applying our 90 years of knowledge of corn biology to develop the next generation of high-quality waxy corn hybrids for the benefit of the entire value chain from growers to processors and end users," said Neal Gutterson, vice president, research and development for DuPont Pioneer. "Starting with an identity-preserved product as our initial CRISPR-Cas offering allows us to lay a solid foundation for success of future larger volume products from this plant breeding innovation." Pioneer is the leading supplier of waxy corn hybrids globally. In the United States, about a half-million acres of waxy corn are grown each year; however, they traditionally yield less than non-waxy corn hybrids. Waxy corn produces a high amylopectin starch content, which is milled for a number of everyday consumer food and non-food uses including processed foods, adhesives and high-gloss paper. Waxy corn is typically grown on contract through a closed-loop production system commonly referred to as "identity-preserved." "The next generation of waxy hybrids developed with CRISPR-Cas will represent a step-change in how efficiently we bring elite genetic platforms of high-yielding waxy corn to our customers," Gutterson said. The United States Department of Agriculture (USDA) recently (USDA) recently published its response to Pioneer’s "Regulated Article Letter of Inquiry" stating that it does not consider next-generation waxy corn developed with CRISPR-Cas enabled advanced breeding technology as regulated by USDA Biotechnology Regulatory Services.
This is worth following.
Dupont Pioneer had announced a major effort worth the look.
DuPont Pioneer today announced waxy corn hybrids as its first commercial agricultural product developed through the application of CRISPR-Cas enabled advanced breeding technology. This next generation of elite waxy corn hybrids is expected to be available to U.S. growers within five years, pending field trials and regulatory reviews. "We’re applying our 90 years of knowledge of corn biology to develop the next generation of high-quality waxy corn hybrids for the benefit of the entire value chain from growers to processors and end users," said Neal Gutterson, vice president, research and development for DuPont Pioneer. "Starting with an identity-preserved product as our initial CRISPR-Cas offering allows us to lay a solid foundation for success of future larger volume products from this plant breeding innovation." Pioneer is the leading supplier of waxy corn hybrids globally. In the United States, about a half-million acres of waxy corn are grown each year; however, they traditionally yield less than non-waxy corn hybrids. Waxy corn produces a high amylopectin starch content, which is milled for a number of everyday consumer food and non-food uses including processed foods, adhesives and high-gloss paper. Waxy corn is typically grown on contract through a closed-loop production system commonly referred to as "identity-preserved." "The next generation of waxy hybrids developed with CRISPR-Cas will represent a step-change in how efficiently we bring elite genetic platforms of high-yielding waxy corn to our customers," Gutterson said. The United States Department of Agriculture (USDA) recently (USDA) recently published its response to Pioneer’s "Regulated Article Letter of Inquiry" stating that it does not consider next-generation waxy corn developed with CRISPR-Cas enabled advanced breeding technology as regulated by USDA Biotechnology Regulatory Services.
This is worth following.
Labels:
CRISPR
Happy Asteroid Day!
Yes, today is Asteroid Day. NASA has announced this event. Look up....it will distract you from Washington!
Labels:
NASA
Monday, June 26, 2017
CBO Healthcare and Facts
The current debate in Healthcare is again filled with junk "facts". The CBO claims:
The Senate bill would increase the number of people who are uninsured by 22 million in 2026 relative to the number under current law, slightly fewer than the increase in the number of uninsured estimated for the House-passed legislation. By 2026, an estimated 49 million people would be uninsured, compared with 28 million who would lack insurance that year under current law.
Now the Census Bureau notes:
The total U.S. population is projected to increase by 98.1 million between 2014 and 2060. As shown in Figure 1, the population is expected to increase from just under 319 million in 2014 to just under 417 million in 2060. This corresponds to an average increase of 2.1 million people per year.
This means that we will be well over 350 million by 2026. We just reached 325 million as of this week! Thus 22 million of 350 million is 6% of the population who will be off Medicaid! This is less than what the ACA put on Medicaid.
These numbers are utter nonsense. I expect the Press in all its ignorant glory will spin this nonsense with no reference to the facts!
The Senate bill would increase the number of people who are uninsured by 22 million in 2026 relative to the number under current law, slightly fewer than the increase in the number of uninsured estimated for the House-passed legislation. By 2026, an estimated 49 million people would be uninsured, compared with 28 million who would lack insurance that year under current law.
Now the Census Bureau notes:
The total U.S. population is projected to increase by 98.1 million between 2014 and 2060. As shown in Figure 1, the population is expected to increase from just under 319 million in 2014 to just under 417 million in 2060. This corresponds to an average increase of 2.1 million people per year.
This means that we will be well over 350 million by 2026. We just reached 325 million as of this week! Thus 22 million of 350 million is 6% of the population who will be off Medicaid! This is less than what the ACA put on Medicaid.
These numbers are utter nonsense. I expect the Press in all its ignorant glory will spin this nonsense with no reference to the facts!
Labels:
Health Care
Saturday, June 24, 2017
Science and Politics?
There seems to be an almost explosive growth of using "science" as a tool for politics. The NEJM has an article by a member of the former Presidents Transition Team berating alleged new participants in the current Administration.
NEJM facilitated the following rant:
Reasonable people may disagree about how to interpret data, but they do not ignore scientific method by giving credence to flawed, fraudulent, or misrepresented studies. They may disagree about the moral significance of fertilization, but they do not delete implantation from the stages of pregnancy and do not confuse the public debate by conflating opposition to abortion with opposition to contraception. They may disagree about the morality of using cadaveric fetal tissue for research, but they do not claim that it is useless. Ignoring, denying, or reimagining reality has real consequences for public policy and human health. Whether in the debates regarding climate change, evolutionary theory, or human reproduction, alternative facts are just fiction, and alternative science is just bad policy.
Now this person, the writer, a Law Professor somewhere out West, argues against some current appointees regarding birth control. I do not know any of the parties but I do claim a bit of logic. All of the references she uses are from the left wing press, not a single one from one of her alleged offenders. Frankly any attorney knows that you use the words of the alleged offending party, at least somewhere!
All her claims are without merit unless she can spell out in the words of the alleged offenders. Lawyers do not make scientists but at least lawyers use facts. This article seems to me to be totally devoid of any facts substantiating directly her claims.
The other dimensions are also the presence of and domination by former elected politicians now holding the mantle of scientific hierarchy, like that of the AAAS, and using that position in my opinion as a means to position their political views.
Eight years ago the battle was over poor economics and shaky healthcare, now we seem to be battling over made up religions, holding the other party out to be Satan! Grow up folks.
NEJM facilitated the following rant:
Reasonable people may disagree about how to interpret data, but they do not ignore scientific method by giving credence to flawed, fraudulent, or misrepresented studies. They may disagree about the moral significance of fertilization, but they do not delete implantation from the stages of pregnancy and do not confuse the public debate by conflating opposition to abortion with opposition to contraception. They may disagree about the morality of using cadaveric fetal tissue for research, but they do not claim that it is useless. Ignoring, denying, or reimagining reality has real consequences for public policy and human health. Whether in the debates regarding climate change, evolutionary theory, or human reproduction, alternative facts are just fiction, and alternative science is just bad policy.
Now this person, the writer, a Law Professor somewhere out West, argues against some current appointees regarding birth control. I do not know any of the parties but I do claim a bit of logic. All of the references she uses are from the left wing press, not a single one from one of her alleged offenders. Frankly any attorney knows that you use the words of the alleged offending party, at least somewhere!
All her claims are without merit unless she can spell out in the words of the alleged offenders. Lawyers do not make scientists but at least lawyers use facts. This article seems to me to be totally devoid of any facts substantiating directly her claims.
The other dimensions are also the presence of and domination by former elected politicians now holding the mantle of scientific hierarchy, like that of the AAAS, and using that position in my opinion as a means to position their political views.
Eight years ago the battle was over poor economics and shaky healthcare, now we seem to be battling over made up religions, holding the other party out to be Satan! Grow up folks.
Labels:
Health Care
Propaganda
It is worth re-reading Bernays on Propaganda, one of the many Wilson employed as Government workers to press his cause for War. As Bernays starts:
The conscious and intelligent manipulation of the organized habits and opinions of the masses is an important element in democratic society. Those who manipulate this unseen mechanism of society constitute an invisible government which is the true ruling power of our country. We are governed, our minds molded, our tastes formed, our ideas suggested, largely by men we have never heard of. This is a logical result of the way in which our democratic society is organized. Vast numbers of human beings must cooperate in this manner if they are to live together as a smoothly functioning society. Our invisible governors are, in many cases, unaware of the identity of their fellow members in the inner cabinet. They govern us by their qualities of natural leadership, their ability to supply needed ideas and by their key position in the social structure. Whatever attitude one chooses toward this condition, it remains a fact that in almost every act of our daily lives, whether in the sphere of politics or business, in our social conduct or our ethical thinking, we are dominated by the relatively small number...
The Government, either the elected or the "Deep State" has mastered the means to control, not just influence, the opinions of the masses. What is especially interesting is that scientists, whose life is supposedly dedicated to questioning, all too often fall into the line of the echo chamber, the desired propagandist focus. Kuhn in his work on Scientific Revolutions looked at this as the paradigm trap.
One should spend more time reading Alice in Wonderland and question the Rabbit Holes, and that nothing is necessarily what it appears to be.
Propaganda is a trade craft practiced by nations, the US as well as Russia, China, and even ISIS. One should always question, especially scientists. Yet there seems to be a lemming effect at play.
Suggestion: step back and examine the "facts", and ask if they are even the true "facts".
The conscious and intelligent manipulation of the organized habits and opinions of the masses is an important element in democratic society. Those who manipulate this unseen mechanism of society constitute an invisible government which is the true ruling power of our country. We are governed, our minds molded, our tastes formed, our ideas suggested, largely by men we have never heard of. This is a logical result of the way in which our democratic society is organized. Vast numbers of human beings must cooperate in this manner if they are to live together as a smoothly functioning society. Our invisible governors are, in many cases, unaware of the identity of their fellow members in the inner cabinet. They govern us by their qualities of natural leadership, their ability to supply needed ideas and by their key position in the social structure. Whatever attitude one chooses toward this condition, it remains a fact that in almost every act of our daily lives, whether in the sphere of politics or business, in our social conduct or our ethical thinking, we are dominated by the relatively small number...
The Government, either the elected or the "Deep State" has mastered the means to control, not just influence, the opinions of the masses. What is especially interesting is that scientists, whose life is supposedly dedicated to questioning, all too often fall into the line of the echo chamber, the desired propagandist focus. Kuhn in his work on Scientific Revolutions looked at this as the paradigm trap.
One should spend more time reading Alice in Wonderland and question the Rabbit Holes, and that nothing is necessarily what it appears to be.
Propaganda is a trade craft practiced by nations, the US as well as Russia, China, and even ISIS. One should always question, especially scientists. Yet there seems to be a lemming effect at play.
Suggestion: step back and examine the "facts", and ask if they are even the true "facts".
Labels:
Commentary
Saturday, June 17, 2017
PSA Testing
I bought my first copy of Scientific American in early May of 1960 on a news stand on Lexington and 52nd Street. I had just returned from my NYC Lifeguard course, and also awaited my being sent to Coney Island. But now I had this window to science. Each article was an opening to some new state of the art discussion. Written by the best of the best and in a manner which assumed you had some reasonable basis to understand. I worked really hard to meet the demands of the authors. I read and reread each article to understand it. I took what little money I had from being a Lifeguard and bought a subscription. I kept it until the magazine turned into something just worse than Time. It became, about in the year 2000, a rag, at least in my opinion. Too bad, it was a window to science, but along came the Internet so who really needed it anyhow.
So I ran across a rant by some person in Scientific American bemoaning the PSA test. He states:
I recently had an awkward conversation with my doctor. I was getting a routine physical, and he recommended that I get a PSA test for prostate cancer. I’m 63. I told him the PSA test harms more men than it helps. He acknowledged that PSA tests produce false positives, but he insisted that follow-up tests and biopsies will determine whether you really have a life-threatening cancer. He knew someone whose life had just been saved by the test. When I still declined to get tested, he looked as though he felt sorry for me. He should feel sorry for the millions of men who have gotten unnecessary biopsies, surgery and radiation as a result of taking the PSA test.
Having written and done work in this area, yes go check me out if you don't believe me, I see that the PSA has substantial merit. The harms are all too often in ones head. A bit of hematuria, some slight discomfort, but overall not that bad. My dentist is worse! Really worse.
He continues:
Just to be clear: you are 240-120 times more likely to misdiagnosed as a result of a positive PSA test and 80-40 times more likely to get unnecessary surgery or radiation than you are to have your life saved.
I do not know where this came from. It seems to imply that of the 240 high PSA tests and PSA velocities done only one in 240 yields a positive PCa. Not in any tests I have seen, and no basis for the claim.
He also states:
In 2012, the U.S. Preventive Services Task Force, a federally funded panel of experts, recommended against the PSA test, saying the cons outweighed the pros. The decision was based primarily on data from two large studies, one done in the U.S., which found that screening did not reduce mortality, and the other in Europe, which showed a modest reduction.
Well first, the two trials had fatal flaws which we and others have discussed at length. Second, the USPSTF is NOT a panel of experts on PCa. They are what I would call a "fishing, drinking and smoking" club of some physicians and others politically connected who have been allowed to opine and now control our health care! There was not a single urologist on the panel.
I would suspect that some sixty years ago Scientific American would have had some set of experts opine. Now they have some fellow with an attitude. Good luck young man!
So I ran across a rant by some person in Scientific American bemoaning the PSA test. He states:
I recently had an awkward conversation with my doctor. I was getting a routine physical, and he recommended that I get a PSA test for prostate cancer. I’m 63. I told him the PSA test harms more men than it helps. He acknowledged that PSA tests produce false positives, but he insisted that follow-up tests and biopsies will determine whether you really have a life-threatening cancer. He knew someone whose life had just been saved by the test. When I still declined to get tested, he looked as though he felt sorry for me. He should feel sorry for the millions of men who have gotten unnecessary biopsies, surgery and radiation as a result of taking the PSA test.
Having written and done work in this area, yes go check me out if you don't believe me, I see that the PSA has substantial merit. The harms are all too often in ones head. A bit of hematuria, some slight discomfort, but overall not that bad. My dentist is worse! Really worse.
He continues:
Just to be clear: you are 240-120 times more likely to misdiagnosed as a result of a positive PSA test and 80-40 times more likely to get unnecessary surgery or radiation than you are to have your life saved.
I do not know where this came from. It seems to imply that of the 240 high PSA tests and PSA velocities done only one in 240 yields a positive PCa. Not in any tests I have seen, and no basis for the claim.
He also states:
In 2012, the U.S. Preventive Services Task Force, a federally funded panel of experts, recommended against the PSA test, saying the cons outweighed the pros. The decision was based primarily on data from two large studies, one done in the U.S., which found that screening did not reduce mortality, and the other in Europe, which showed a modest reduction.
Well first, the two trials had fatal flaws which we and others have discussed at length. Second, the USPSTF is NOT a panel of experts on PCa. They are what I would call a "fishing, drinking and smoking" club of some physicians and others politically connected who have been allowed to opine and now control our health care! There was not a single urologist on the panel.
I would suspect that some sixty years ago Scientific American would have had some set of experts opine. Now they have some fellow with an attitude. Good luck young man!
Labels:
Cancer
Sur Le Pont d'Avignon, tout le monde y danse, danse!
It is most likely the case that any child who learned French also learned this little ditty. All the world danced across the bridge in Avignon. And at the heart of the dance was John XXII, the Bishop of Rome, And at the heart of the juristic proceedings coming from Avignon, the New Babylon, were those that inspired William of Ockham and Marsilius of Padua. It was the arrogance of the then Bishop of Rome which led to the development of Individualism and the ideas that lent substance to Montesquieu.
For some reason the current Bishop of Rome is celebrating the 700th anniversary of this event. As the Vatican notes:
Pope Francis has appointed Cardinal Paul Poupard as his special envoy to the celebrations of the 700th anniversary of the enclave of the Popes in Avignon, France. Cardinal Poupard is the president-emeritus of the Pontifical Council for Culture. He will be accompanied at the 23-25 June event by Msgr. Jean-Marie Gérard, vicar general of Avignon, and Rev. Canon Daniel Bréhier, rector of the Cathedral of Avignon.
Celebrating this event is rather strange since it precipitated the revolt of Luther and all that followed.
What is even more ironic is that it was John XXII who attacked the Franciscans and the Spirituals who felt a need for poverty. After all how could John live in such a lavish castle while the Franciscans alleged the Apostles owned nothing.
This is a celebration of the Papacy leaving Rome and commencing its accumulation of massive wealth and its persecution of the Franciscans and other intellectuals. I would have thought that this would be a time for reflection and not one of celebration. Especially for one named Francis.
For some reason the current Bishop of Rome is celebrating the 700th anniversary of this event. As the Vatican notes:
Pope Francis has appointed Cardinal Paul Poupard as his special envoy to the celebrations of the 700th anniversary of the enclave of the Popes in Avignon, France. Cardinal Poupard is the president-emeritus of the Pontifical Council for Culture. He will be accompanied at the 23-25 June event by Msgr. Jean-Marie Gérard, vicar general of Avignon, and Rev. Canon Daniel Bréhier, rector of the Cathedral of Avignon.
Celebrating this event is rather strange since it precipitated the revolt of Luther and all that followed.
What is even more ironic is that it was John XXII who attacked the Franciscans and the Spirituals who felt a need for poverty. After all how could John live in such a lavish castle while the Franciscans alleged the Apostles owned nothing.
This is a celebration of the Papacy leaving Rome and commencing its accumulation of massive wealth and its persecution of the Franciscans and other intellectuals. I would have thought that this would be a time for reflection and not one of celebration. Especially for one named Francis.
Labels:
Papacy
Tuesday, June 13, 2017
You Don't Need Instruments in your Car (Airplane, whatever)
I noted a piece today about monitoring blood sugar for people with Type 2 Diabetes. Frankly it can be "cured" in almost 90% of the cases by loosing wight and keeping BMI less than 23. But who cares, most physicians send the patient off with meds, and let the patient think that if they take the meds they are fine. High blood glucose causes inflammation and inflammation is a major cause of cancer. Thus pushing down the HgA1B is a bit deceptive. The weight is still there. the fat is the inflammatory cause, and off we go.
In a WebMD piece the author states:
People with type 2 diabetes who aren't taking insulin don't necessarily need to check their blood sugar levels, a new study contends. Many of these patients use "finger prick" blood sugar monitors, but "testing blood sugar didn't have any impact on their blood sugar," said study author ......... "The best way to control blood sugar is to take your medication the way your doctor asks you to and to take good care of yourself," she said. "The key is really taking your medications." Monitoring might be helpful when starting a new medication or changing doses, Young said.
Monitoring blood sugar should be the best early warning sign. Even before one starts taking meds. Fasting blood sugar is a red light for improper diet. Those late night cookies, ice cream, soda, cake, etc drive up the FBS. So why not start before one needs meds. It tells you if your oil pressure is dropping, if you are running out of gas, or the altitude is too low.
Pilots make mistakes when the do not pay attention to instruments. The instrument is an early warning signal. Meds are just wearing blinders and hoping for the best. It does not happen.
In a WebMD piece the author states:
People with type 2 diabetes who aren't taking insulin don't necessarily need to check their blood sugar levels, a new study contends. Many of these patients use "finger prick" blood sugar monitors, but "testing blood sugar didn't have any impact on their blood sugar," said study author ......... "The best way to control blood sugar is to take your medication the way your doctor asks you to and to take good care of yourself," she said. "The key is really taking your medications." Monitoring might be helpful when starting a new medication or changing doses, Young said.
Monitoring blood sugar should be the best early warning sign. Even before one starts taking meds. Fasting blood sugar is a red light for improper diet. Those late night cookies, ice cream, soda, cake, etc drive up the FBS. So why not start before one needs meds. It tells you if your oil pressure is dropping, if you are running out of gas, or the altitude is too low.
Pilots make mistakes when the do not pay attention to instruments. The instrument is an early warning signal. Meds are just wearing blinders and hoping for the best. It does not happen.
Labels:
Diabetes,
Health Care
Monday, June 12, 2017
FED Balance Sheet
Every once in a while it is worth looking at the FED Balance Sheet. Here is the core values.
This is what it would look like if the FED just did FED business, BUT!
We still have this mess. $@.5 trillion or so of normal like stuff and $2 trillion of that old mortgage backed securities the FED soaked up. They may be really worth nothing!
So what does it add up to. This is a Bernake, Yellen, Obama ticking time bomb on the financial markets. Could this $2 trillion in junk be sold for anything? They have never even asked. So who will?
This is what it would look like if the FED just did FED business, BUT!
We still have this mess. $@.5 trillion or so of normal like stuff and $2 trillion of that old mortgage backed securities the FED soaked up. They may be really worth nothing!
So what does it add up to. This is a Bernake, Yellen, Obama ticking time bomb on the financial markets. Could this $2 trillion in junk be sold for anything? They have never even asked. So who will?
Labels:
Economy
Employment
The above is a summary of the recent employment. The following curve is of interest.
It says that based on 2006 stats we have some 3 million plus still not even counted! The actual unemployment using 2006 base of workers is 6.5%. The decrease is constant but we have a long way to go.
Next we will look at the mix.
Next we will look at the mix.
Labels:
Economy
Sunday, June 11, 2017
Science and Engineering vs Religion?
Carbon dioxide is emitted by a variety of natural and man made systems. Energy generation as currently deployed uses a great deal of CO2 producing sources such as coal. In a recent Science piece there is an alternative proposed to recycle the CO2 for zero emissions.
They state:
In contrast, NET Power, the startup backing the new plant, says it expects to produce emission-free power at about $0.06 per kilowatt-hour. That's about the same cost as power from a state-of-the-art natural gas-fired plant—and cheaper than most renewable energy. The key to its efficiency is a new thermodynamic cycle that swaps CO2 for the steam that drives turbines in conventional plants. Invented by an unlikely trio—a retired British engineer and a pair of technology geeks who had tired of their day jobs—the scheme may soon get a bigger test. If the prototype lives up to hopes, NET Power says, it will forge ahead with a full-scale, 300-megawatt power plant—enough to power more than 200,000 homes—which could open in 2021 at a cost of about $300 million. Both the company and CCS experts hope that the technology will then proliferate. “This is a game-changer if they achieve 100% of their goals,” says John Thompson, a carbon capture expert at the Clean Air Task Force, an environmental nonprofit with an office in Carbondale, Illinois.
If this works it is a great step forward and involves no Carbon tax or belief in world ending events.
I guess something else will come along. Some people need to have an event to end the world and somehow scientists and engineers always burst their balloon. Who was that guy who said population would end life as we know it?
The only real ender is a bunch of nuclear weapons...remember that!
They state:
In contrast, NET Power, the startup backing the new plant, says it expects to produce emission-free power at about $0.06 per kilowatt-hour. That's about the same cost as power from a state-of-the-art natural gas-fired plant—and cheaper than most renewable energy. The key to its efficiency is a new thermodynamic cycle that swaps CO2 for the steam that drives turbines in conventional plants. Invented by an unlikely trio—a retired British engineer and a pair of technology geeks who had tired of their day jobs—the scheme may soon get a bigger test. If the prototype lives up to hopes, NET Power says, it will forge ahead with a full-scale, 300-megawatt power plant—enough to power more than 200,000 homes—which could open in 2021 at a cost of about $300 million. Both the company and CCS experts hope that the technology will then proliferate. “This is a game-changer if they achieve 100% of their goals,” says John Thompson, a carbon capture expert at the Clean Air Task Force, an environmental nonprofit with an office in Carbondale, Illinois.
If this works it is a great step forward and involves no Carbon tax or belief in world ending events.
I guess something else will come along. Some people need to have an event to end the world and somehow scientists and engineers always burst their balloon. Who was that guy who said population would end life as we know it?
The only real ender is a bunch of nuclear weapons...remember that!
Labels:
Global Warming
Wednesday, June 7, 2017
Public Private Partnerships
I have considered these several time with ultimately no positive results. The mindset of the civil servant is orthogonal to that of the business person, especially an entrepreneur.
An entrepreneur will take risks, their own time and money, and seek a return on that investment if possible. A civil servant is risk averse. They want to get as much as they can for nothing and never want to endanger their pensions. An entrepreneur has no pension and does not get paid.
A decade ago I tried this with a town in New Hampshire and the result was a loss of many dollars and time. The town could never agree to anything. In fact the Board demanded free service for its "poor" residents, and my comment was "show me one and I will pay personally for their service". Needless to say it went no where.
The NY Times discusses this concept and the article states:
Whether through fees like parking meters and tolls on a road, or through government payments to the contractors, such projects are ultimately supported by taxpayers.
Now read this statement very carefully. Taxpayers support it even if there are tolls or meters! Now just think, yes think, what the words mean and are saying. If the user is paying, which is what we see in a real economy, then the taxpayer pays only as a user, NOT as a taxpayer. That is basic logic. But somehow the writer states the opposite, namely the statement is at face wrong! The writer in my opinion must be clueless!
An entrepreneur will take risks, their own time and money, and seek a return on that investment if possible. A civil servant is risk averse. They want to get as much as they can for nothing and never want to endanger their pensions. An entrepreneur has no pension and does not get paid.
A decade ago I tried this with a town in New Hampshire and the result was a loss of many dollars and time. The town could never agree to anything. In fact the Board demanded free service for its "poor" residents, and my comment was "show me one and I will pay personally for their service". Needless to say it went no where.
The NY Times discusses this concept and the article states:
Whether through fees like parking meters and tolls on a road, or through government payments to the contractors, such projects are ultimately supported by taxpayers.
Now read this statement very carefully. Taxpayers support it even if there are tolls or meters! Now just think, yes think, what the words mean and are saying. If the user is paying, which is what we see in a real economy, then the taxpayer pays only as a user, NOT as a taxpayer. That is basic logic. But somehow the writer states the opposite, namely the statement is at face wrong! The writer in my opinion must be clueless!
Labels:
Government
Hugs?
The Guardian has an interesting piece in "hugs". They note:
When will Jerry Seinfeld learn about hugging? Given that his celebrated sitcom’s unsentimental tone was based on their “no hugging, no learning” writers’ room maxim, possibly never. And, clearly, time is running out if a recent encounter with Kesha is anything to go by. Seinfeld was being interviewed by US radio host Tommy McFly at an event in Washington DC on Tuesday, when the pop star interrupted them to announce: “Oh my gosh, I love you so much.” “Oh, thanks,” said Jerry.
”Can I give you a hug?” asked Kesha. “No, thanks,” Seinfeld said.
This is interesting since I spent last weekend at one of my grandson's graduations where the Episcopal, read Church of England, Oxford educated, headmaster hugged each and every graduate! It would have been child abuse a decade ago!
Now I am from the older generation where even "kissing" was frowned upon, germs I was told. Hugs! Why the other fellow could stab you in the back, especially if you were in Washington. Professional full time GS-12 backstabbers all over!
The first time I cam to this hugging thing was a friend who lives in San Francisco who came to New York and greeted me with a hung, in the middle of Manhattan. Yes the crowd around look at bit askance, it was an investment bank after all. But in San Francisco one is expected to do the extreme. New York on the other hand is truly a social conservative holdout. We do not even acknowledge others on an elevator!
When will Jerry Seinfeld learn about hugging? Given that his celebrated sitcom’s unsentimental tone was based on their “no hugging, no learning” writers’ room maxim, possibly never. And, clearly, time is running out if a recent encounter with Kesha is anything to go by. Seinfeld was being interviewed by US radio host Tommy McFly at an event in Washington DC on Tuesday, when the pop star interrupted them to announce: “Oh my gosh, I love you so much.” “Oh, thanks,” said Jerry.
”Can I give you a hug?” asked Kesha. “No, thanks,” Seinfeld said.
This is interesting since I spent last weekend at one of my grandson's graduations where the Episcopal, read Church of England, Oxford educated, headmaster hugged each and every graduate! It would have been child abuse a decade ago!
Now I am from the older generation where even "kissing" was frowned upon, germs I was told. Hugs! Why the other fellow could stab you in the back, especially if you were in Washington. Professional full time GS-12 backstabbers all over!
The first time I cam to this hugging thing was a friend who lives in San Francisco who came to New York and greeted me with a hung, in the middle of Manhattan. Yes the crowd around look at bit askance, it was an investment bank after all. But in San Francisco one is expected to do the extreme. New York on the other hand is truly a social conservative holdout. We do not even acknowledge others on an elevator!
Labels:
Commentary
ASCO and PCa
In an ASCO report commenting on the USPSTF D rating for PSA testing the report states:
In 2012, PSA screening for prostate cancer (CaP) detection was given a “Grade D” recommendation for all men by the USPSTF. Recent U.S. studies report declines in PSA screening with concomitant increases in advanced CaP at diagnosis. This study examined the association between PSA screening history and CaP aggressiveness in a racially diverse, military cohort with equal health care access.... In this RP cohort, higher risk stratum, increased GU, and poorer BCR-free survival were associated with no PSA screening history. BCR-free survival was incrementally worsened by less PSA screening. A complete absence of PSA screening may lead to more aggressive disease at presentation and poorer clinical outcomes.
This was a Government conducted study, by people apparently competent in the field. This is just another study confirming the deadly results of following USPSTF.
In 2012, PSA screening for prostate cancer (CaP) detection was given a “Grade D” recommendation for all men by the USPSTF. Recent U.S. studies report declines in PSA screening with concomitant increases in advanced CaP at diagnosis. This study examined the association between PSA screening history and CaP aggressiveness in a racially diverse, military cohort with equal health care access.... In this RP cohort, higher risk stratum, increased GU, and poorer BCR-free survival were associated with no PSA screening history. BCR-free survival was incrementally worsened by less PSA screening. A complete absence of PSA screening may lead to more aggressive disease at presentation and poorer clinical outcomes.
This was a Government conducted study, by people apparently competent in the field. This is just another study confirming the deadly results of following USPSTF.
Labels:
Cancer
Tuesday, June 6, 2017
Treasury Spreads June 2017
Treasury spreads are flattening out again. Look at the one above for yesterday and it seems to be as flat as one can get before the FED increases the short term rate. Note if the FED does increase the short term we may eventually get to an inverted curve again. The concern should be the long term and the fact that the FED is trying to unload the $4 trillion of junk on its books!
The above provides a good look over the past ten years. Worth thinking about!
The above provides a good look over the past ten years. Worth thinking about!
Labels:
Economy
Monday, June 5, 2017
In the Old Days, or "When I was your age"
The NY Times has posted a piece from a Campus Security Guard in England. Now my first cut at undergraduate school was in New York City, not London and it was decades ago. My two grandsons are off to college, one going as far as the nearest stop light, the other going halfway cross country. It really is different for them than it was for me.
Back in 1960 I had three roommates, O'Malley, Driscoll, and Gallagher, we could have been an Irish Law Firm, but each was different. We rented a two bedroom apartment on Broadway, nice, new, and $120 per month! That was $30 each per month. Then food was what you collected, and security? There was none. The closest I got was the fact that my father was in the NYPD as was my grandfather and so I had a "cop network" if necessary.
We walked to class and took the subway at odd hours, the Broadway line. One night I met Malcolm X on the train with his group. Said hello, and he got off at 42nd Street. Sort of a Forest Gump moment.
The Brit notes:
Before I started in the job, I had the same image of the campus guard in my head as you did: a bloke too fat for the cops, or a mixed martial-arts nerd. Guards like that exist, but they don’t tend to last. Once they realize you do more talking in this job than throwing punches, and take one look at the salary, they check out. It’s true, the money’s not fantastic, but I wouldn’t want to do anything else. The buzz I get from helping people is up there with scoring a football goal, or perhaps, remembering a password I thought I’d forgotten. Plus, I get to see people shaping their futures every day. Who’d want to swap that for breathing office air?
When I spent a decade or so at MIT, during the Viet Nam war riots, I never saw a Campus Cop, but now they are everywhere. I wonder what has happened. Has crime increased or are we becoming global helicopter parents. Sixty years ago you got a $20 bill and a cardboard suitcase. You better have a job or find one, the campus did not give you one out the gate. Today? Kindly Campus Cops!
Back in 1960 I had three roommates, O'Malley, Driscoll, and Gallagher, we could have been an Irish Law Firm, but each was different. We rented a two bedroom apartment on Broadway, nice, new, and $120 per month! That was $30 each per month. Then food was what you collected, and security? There was none. The closest I got was the fact that my father was in the NYPD as was my grandfather and so I had a "cop network" if necessary.
We walked to class and took the subway at odd hours, the Broadway line. One night I met Malcolm X on the train with his group. Said hello, and he got off at 42nd Street. Sort of a Forest Gump moment.
The Brit notes:
Before I started in the job, I had the same image of the campus guard in my head as you did: a bloke too fat for the cops, or a mixed martial-arts nerd. Guards like that exist, but they don’t tend to last. Once they realize you do more talking in this job than throwing punches, and take one look at the salary, they check out. It’s true, the money’s not fantastic, but I wouldn’t want to do anything else. The buzz I get from helping people is up there with scoring a football goal, or perhaps, remembering a password I thought I’d forgotten. Plus, I get to see people shaping their futures every day. Who’d want to swap that for breathing office air?
When I spent a decade or so at MIT, during the Viet Nam war riots, I never saw a Campus Cop, but now they are everywhere. I wonder what has happened. Has crime increased or are we becoming global helicopter parents. Sixty years ago you got a $20 bill and a cardboard suitcase. You better have a job or find one, the campus did not give you one out the gate. Today? Kindly Campus Cops!
Labels:
Commentary
More on CAR-T Cells
We have been following the progress on CAR-T cells over the past few years. The recent result reported in Science Daily is of special import. Namely:
In an early clinical trial, 33 out of 35 (94 percent) patients had clinical remission of multiple myeloma upon receiving a new type of immunotherapy -- chimeric antigen receptor (CAR) T cells targeting B-cell maturation protein or BCMA. Most patients had only mild side effects.
Namely, find a target on the desired cell and then create a "smart bomb" the CAR-T cell, and then set it loose. It seems to be working much more effectively now. It still has some "carpet bombing effects" but this may very well change the paradigm for cancer treatment.
Namely, find a surface target, then construct a patient specific attack element, then let the immune system loose. Very worth while to follow!
In an early clinical trial, 33 out of 35 (94 percent) patients had clinical remission of multiple myeloma upon receiving a new type of immunotherapy -- chimeric antigen receptor (CAR) T cells targeting B-cell maturation protein or BCMA. Most patients had only mild side effects.
Namely, find a target on the desired cell and then create a "smart bomb" the CAR-T cell, and then set it loose. It seems to be working much more effectively now. It still has some "carpet bombing effects" but this may very well change the paradigm for cancer treatment.
Namely, find a surface target, then construct a patient specific attack element, then let the immune system loose. Very worth while to follow!
Labels:
CAR-T Cells
Friday, June 2, 2017
Fair Use and the EU
The EU/EC seems to be an ever expanding set of rules and regulations that at to control people's lives. Fundamentally it represents an entity which denies fundamental American values. The EUs stance as exemplified all too often by the German state, an entity which believes that its policies are all too often to dominate and control.
The most recent example is the intent to control free speech. We in the US have a mandated right to free speech. In the EU it is severely curtailed and controlled.
The EFF just recently notes:
This week, EFF joined Creative Commons, Wikimedia, Mozilla, EDRi, Open Rights Group, and sixty other organizations in signing an open letter [PDF] addressed to Members of the European Parliament expressing our concerns about two key proposals for a new European "Digital Single Market" Directive on copyright. These are the "value gap" proposal to require Internet platforms to put in place automatic filters to prevent copyright-infringing content from being uploaded by users (Article 13) and the equally misguided "link tax" proposal that would give news publishers a right to compensation when snippets of the text of news articles are used to link to the original source (Article 11).
Namely if one is analyzing a work which has been posted and one desires to refer to what was said and then in any way comment, that would be a breach of the proposed law. At best one could refer to the source and then let the reader go and try to find it. Frankly that defeats the ability to have free and open discourse and also makes a mockery of the very essence of the Internet.
The filter proposal also makes the Internet facilitators entities who must on their own filter and control. Pravda did that a while back and you know how that worked.
I suspect it is a mind set. We Americans do not understand Europeans and Europeans do not understand Americans. Both all too often look down on the other and I suspect the gap is widening. One could as if the Paris Accord was reflective of that?
The most recent example is the intent to control free speech. We in the US have a mandated right to free speech. In the EU it is severely curtailed and controlled.
The EFF just recently notes:
This week, EFF joined Creative Commons, Wikimedia, Mozilla, EDRi, Open Rights Group, and sixty other organizations in signing an open letter [PDF] addressed to Members of the European Parliament expressing our concerns about two key proposals for a new European "Digital Single Market" Directive on copyright. These are the "value gap" proposal to require Internet platforms to put in place automatic filters to prevent copyright-infringing content from being uploaded by users (Article 13) and the equally misguided "link tax" proposal that would give news publishers a right to compensation when snippets of the text of news articles are used to link to the original source (Article 11).
Namely if one is analyzing a work which has been posted and one desires to refer to what was said and then in any way comment, that would be a breach of the proposed law. At best one could refer to the source and then let the reader go and try to find it. Frankly that defeats the ability to have free and open discourse and also makes a mockery of the very essence of the Internet.
The filter proposal also makes the Internet facilitators entities who must on their own filter and control. Pravda did that a while back and you know how that worked.
I suspect it is a mind set. We Americans do not understand Europeans and Europeans do not understand Americans. Both all too often look down on the other and I suspect the gap is widening. One could as if the Paris Accord was reflective of that?
Labels:
EU
Thursday, June 1, 2017
The USPSTF
Over the last ten years we have commented upon what we feel is the generally inappropriate direction from the USPSTF. This is the collection of folks who thought that it was fine to do away with PSA testing.
Urotoday has a fantastic video describing the USPSTF and its failings. It is truly worth watching. The first slide shown below is what is iitruly terrifying.
Note that the ACA, known as Obamacare, allows this group of what in my opinion are less than truly qualified folks, to mandate what is proper care. The second slide shown below:
shows that they do so without any accountability.
If one were to have followed the PSA debate, in the professional media or in my writings as noted herein, one would see that the mortality from PCa has exploded since the USPSTF mandated no coverage of PSA testing and its sequellae.
These folks are in my opinion one of the many "Death Panels" established under the ACA. Yes, they denied coverage and people died.
Hopefully Congress will eliminate this, in my opinion, "mad dog" group as well as many others formed under the aegis of the ACA such as PCORI!
Urotoday has a fantastic video describing the USPSTF and its failings. It is truly worth watching. The first slide shown below is what is iitruly terrifying.
USPSTF - ISSUES
• Proceedings
are not required to be made public
• Exempt from
FACA review process
• Exempt from
the Administrative Procedures Act (APA)
• Requires
public disclosure and participation in activities
• Defines
scope of judicial review
• Encompasses:
• The
Freedom of Information Act (FOIA)
• The
Privacy Act
• USPSTF is
only Federal Agency which can set payment policy exempt from FAPA/APA
USPSTF - ISSUES
• Proceedings
are not required to be made public
• Exempt from
FACA review process
• Exempt from
the Administrative Procedures Act (APA)
• Requires
public disclosure and participation in activities
• Defines
scope of judicial review
• Encompasses:
• The
Freedom of Information Act (FOIA)
• The
Privacy Act
• USPSTF is
only Federal Agency which can set payment policy exempt from FAPA/APA
shows that they do so without any accountability.
If one were to have followed the PSA debate, in the professional media or in my writings as noted herein, one would see that the mortality from PCa has exploded since the USPSTF mandated no coverage of PSA testing and its sequellae.
These folks are in my opinion one of the many "Death Panels" established under the ACA. Yes, they denied coverage and people died.
Hopefully Congress will eliminate this, in my opinion, "mad dog" group as well as many others formed under the aegis of the ACA such as PCORI!
Labels:
Cancer,
Government,
Health Care
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