The CancerGene web site is extremely useful. As Eureka notes:
This new data release brings the amount of freely available,
open-access data on the website to 453 cancer treatment compounds, 989
cancer cell lines, 494,973 genomic associations tested and 386,293 drug
dose response curves. The previous study has already enabled discoveries that led to drug
trials of PARP inhibitors in childhood bone cancer, directly contributed
to drug development in the pharmaceutical industry and powered 70
research studies across the globe. The datasets are accessed by over 350
users each day and this is set to increase with the new data release.
The project team hope that this enhanced resource will help to power new
discoveries and therapeutic options for many years to come. The Genomics of Drug Sensitivity in Cancer project is a pioneering
public-private partnership funded by Wellcome. It combines samples of
hospital patients' cancer cell lines with licensed and experimental
cancer drugs from a number of pharmaceutical companies, and applies
in-depth observation and genetic analysis to identify how the underlying
changes in a person's DNA affect how they will respond to treatment.
The ultimate goal is to identify biomarkers that could be used in the
clinic to identify which drugs will work best to treat a patient's
cancer, based on the tumour's genetic profile.
This definitely worth a look.
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A blog containing opinion and analysis in a wide array of areas including the economy, health care, broadband and international relations.
About Me
- Florham Park, NJ, United States
- Terry has spent most of his career in industry, half in corporate executive positions, and half involved in his start ups. He started on the Faculty and Staff at MIT in 1967 and was there until 1975, and he had returned to MIT from 2005 to 2012 to assist groups of doctoral and post doc students. Terry has focused on a broad set of industries from cable, to satellite, wireless, and even health care software and medical imaging. Terry has published extensively in a broad set of areas as well as having written several books. Terry has returned to Medicine on Boards at Columbia University Medical Center. Copyright 2008-2024 Terrence P McGarty all rights reserved. NOTE: This blog contains personal opinions of the author and is not meant in any manner to provide professional advice, medical advice, legal advice, financial advice. Reliance on any of the opinions contained herein is done at the risk of the user. For publications see: https://www.researchgate.net/profile/Terrence_Mcgarty
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