We have just posted a paper discussing the variants and vaccines. The paper notes:
Viral variants have been developing in COVID-19 and especially in the spike protein. In order to address these changes one must also modify the vaccines currently being produced. There are several ways to do this. One is the classic post hoc manner of monitoring what is produced and then address it. The second extreme is pre hoc, anticipating what most likely will occur and vaccinate against this anticipated variant. We present a proposal for a Bayesian pre hoc approach to vaccine development with COVID-19 variants.
This is the sixth in a series of COVID-19 papers prepared over the past year. Interest in these has to my surprise stretched even to the Wuhan Viral Institute. Also the one written last April on therapeutics has now been validated on NEJM by several authors.
Comments are always welcome.
Posts
